Lauren and Wendy Nolan-Sellers readily admitted they were scared when they quit their day jobs in 2012 to launch a home-design company.

The career trajectory of out author Anne Balay is flush with detours. It starts with an English Ph.D., shifts to car mechanic and transitions back to teaching. Then, there’s a book written, tenure denied — and a sharp turn to professional truck driver.

UP CLOSE AND PERSONAL: Enduring out folk/rock duo Indigo Girls return for two intimate performances Oct. 11-12 at Keswick Theatre, 291 N. Keswick Ave. in Glenside. For more information or tickets, call 215-572-7650.

A guitarist in blood-red Chelsea boots strums a duh-nuh-nuh-nuh-nuh as a front woman decked in Brit punk plaid struts to the front row and belts out:

“We are The Preventers! And we are here to save youuuuuuuu!”

Comedian, actress and dish queen Kathy Griffin is no stranger to controversy, but this year she finds herself back from celebrity exile after drawing the fiery and somewhat hypocritical wrath of the political establishment, media and the entertainment industry last year for a satirical photo she took depicting her holding the severed, bloody head of Presdient Donald Trump. The result was quick and decisive, as representatives for venues and networks across the country rushed to cut ties and cancel upcoming gigs.

There’s a lot of misfit action rampant at Plays & Players in October. The theater’s long-running tenant, 1812 Productions, just happens to be this city’s sole company purely dedicated to all things comic. British playwright Tom Wells writes about his gray industrial hometown of Hull, England with misfit-driven plays about escapism such as “Folk,” “Jumpers for Goalposts” and now “Broken Biscuits,” which has its American premiere at 1812 in October.

Every fall for the past three years, CAMP Rehoboth Community Center hosts a giant block party in the legendarily gay-friendly beach town.

Along with Rehoboth’s vibrant restaurant scene comes its reputation for live entertainment.

I love Eastern State Penitentiary, not just at Halloween but all year. The staff does a lot of work educating people about prison reform and the history of incarceration in the United States and around the world. They work with artists and activists and contribute a lot to the community. Through this column, I’ve had the pleasure of meeting many cool people who work there, usually around this time of year when ESP flips to Terror Behind the Walls. One of the top-rated haunted attractions in the country, it’s set in the massive, castle-like former prison where outlaws like Al Capone were incarcerated.

Fred Hersch has spent the better part of his career building a reputation as one of the most prominent pianists and composers in the somewhat-rarified realm of modern jazz. What surprised him was that, along the way, he’d make history.

UP WITH PEOPLE: Circa, the contemporary and highly acrobatic circus troupe from Australia, returns to the Annenberg Center with the U.S. premiere of “Humans,” about the power of physical and emotional strength, Sept. 28-29 at Zellerbach Theatre, 3680 Walnut St. For more information or tickets, call 215-898-3900. Photo: Pedro Greig

’Tis the season for a certain orange fruit — before you get all excited by the name, we need to tell you there’s no pumpkin in any considerable quantity on the menu. Yes, you get a packet of roasted pumpkin seeds at the end of your meal. But we found out that “Pumpkin” is the pet name chefs and owners Ian Moroney and Hillary Bor have for each other.